The multifaceted contribution of platelets in the emergence and aftermath of acute cardiovascular events

Atherosclerosis is an underlying cause of a broad array cardiovascular diseases characterized by plaques, arterial wall thickening initiated hyperlipidemia, pro-inflammatory signals, endothelial dysfunction and the influx inflammatory cells. By still incompletely mechanisms, these plaques can destabilize or erode, leading to thrombosis blood vessel occlusion becomes clinically manifest as angina pectoris, myocardial infarction (MI) stroke.Among several cell types that are involved in development atherosclerosis, role platelets during thrombotic ruptured eroded well established exploited evident extensive use platelet inhibitors. However, there increasing evidence also earlier stages atheroma exhibiting activities. The scope this review describe initiation propagation atherosclerosis beyond; atherothrombotic complications.